The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated Research Assistant to join the Molecular Mechanisms of Retinal Diseases Group.
The Molecular Mechanisms of Retinal Diseases Group investigates the molecular processes driving retinal cell types and their dysfunction in genetic diseases. The research assistant will collaborate with postdoctoral fellows, students, and researchers by performing biochemical, molecular, and cell biology analyses of retinal disease-related pathomechanisms using animal models, retina cultures, and human stem cell-derived retinal organoids.
IOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss. It is a place where your expertise will be valued, your abilities challenged, and your knowledge expanded.
- Molecular and cellular analysis of RNA and protein expression, RNA-protein and protein-protein interactions
- Culture and manipulation of primary mammalian cell (using CRISPR/Cas9, RNAi)
- Vector construction and molecular cloning
- Tissue cryosectioning, immunohistochemistry and fluorescent microscopy
- Work directly with in vivo small animal models of human eye diseases
- Involvement in lab management and organization
- Biologielaborant/in (or equivalent education) with several years of work experience or Bachelor’s/Master’s Degree (or equivalent) in molecular biology or related field
- Relevant work experience with cell cultures and mouse models
- Independence in the planning, conductance, analysis and troubleshooting of standard molecular biology experiments
- Enthusiasm to establish and optimize new protocols and techniques
- Highly organized, detail-oriented and skilled with computers
- Good written and verbal communications skills
- Fluency in oral and written English and German